おすすめの製品
アッセイ
97%
フォーム
solid
mp
77-79 °C (lit.)
官能基
chloro
phenyl
保管温度
2-8°C
SMILES記法
ClCc1ccc(OCc2ccccc2)cc1
InChI
1S/C14H13ClO/c15-10-12-6-8-14(9-7-12)16-11-13-4-2-1-3-5-13/h1-9H,10-11H2
InChI Key
UYQPSKUPEXAQRJ-UHFFFAOYSA-N
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詳細
4-(Benzyloxy)benzyl chloride acts as a solid support to readily determine the loading of the corresponding polymer-bound acids by direct cleavage. This was determined while studying the coupling of substituted aromatic, heterocyclic, and alkyl carboxylates to the resin.
アプリケーション
4-(benzyloxy)benzyl chloride is used in the preparation of 4-aryl-3,4-dihydropyrimidine-5-carboxylates (DHPMs) which exhibits a wide spectrum of biological effects.
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Skin Corr. 1B
保管分類コード
8A - Combustible corrosive hazardous materials
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
114081-25G:
114081-BULK:
114081-5G:
114081-1G:
114081-VAR:
C O Kappe
Bioorganic & medicinal chemistry letters, 10(1), 49-51 (2000-01-15)
A series of pharmacologically active, functionalized 4-aryl-3,4-dihydropyrimidine-5-carboxylates (DHPMs) are prepared by a versatile novel solid phase approach. In the key step, a polymer-bound thiouronium salt is condensed with unsaturated 1-ketoesters. The resulting polymer bound 1,4-dihydropyrimidines are cleaved from the resin
Jianbo Li et al.
Drug delivery, 25(1), 1117-1126 (2018-05-22)
Asthma is one of the most prevalent chronic inflammatory diseases of lung. Current asthma therapy using inhaled corticosteroid often results in undesired treatment outcome due to poor compliance and drugs' lack of tissue specificity. N,N,N'-trimethyl-N'-(2-hydroxyl-3-methyl-5-123Iiodobenzyl)-1,3-propanediamine (HIPD), a phenolic propanediamine derivative
Crist N Filer et al.
Journal of labelled compounds & radiopharmaceuticals, 62(1), 24-27 (2018-07-15)
The 2-step synthesis of [1-14 C]tyramine hydrochloride is described with the product being characterized by TLC, HPLC, and UV spectroscopy. Several methods are provided to purify [1-14 C]tyramine hydrochloride, and its storage and stability are also discussed.
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