コンテンツへスキップ
Merck

TNFRSF11A

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

別名:
CD265, FEO, LOH18CR1, ODFR, OFE, OPTB7, OSTS, PDB2, RANK, TRANCER
Species:
UniProtKB ID:
遺伝子ID:
  • Human(8792) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
  • Mouse(21934) tumor necrosis factor receptor superfamily, member 11a
  • Rat(498206) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • cow(530884) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • sheep(101118842) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • naked mole-rat(101718050) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • Domestic Rabbit(100358260) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • domestic guinea pig(100724119) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • chicken(769909) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • dog(483957) tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • domestic cat(101090651) tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

製品番号
詳細
Species
Human TNFRSF11A ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-TNFRSF11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-TNFRSF11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot

Proteins

製品番号
詳細
Species
sRank レセプター ヒト, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
RANK/Fcキメラ マウス由来, ≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
mouse