SESN1
sestrin 1
別名:
PA26, SEST1
Species:
Human SESN1 (27244), Mouse Sesn1 (140742), Rat Sesn1 (294518), Zebrafish sesn1 (436933), domestic cat SESN1 (101099380), dog SESN1 (481956), chicken SESN1 (421766), cow SESN1 (538226), sheep SESN1 (101115970), naked mole-rat Sesn1 (101699483)
UniProtKB ID:
遺伝子ID:
- Human(27244) Summary: This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
- Mouse(140742) sestrin 1
- Rat(294518) sestrin 1
- Zebrafish(436933) sestrin 1
- domestic cat(101099380) sestrin 1
- dog(481956) sestrin 1
- chicken(421766) sestrin 1
- cow(538226) sestrin 1
- sheep(101115970) sestrin 1
- naked mole-rat(101699483) sestrin 1
- domestic guinea pig(100713452) sestrin 1
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-sestrin 1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
western blot
抗SESN1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗SESN1抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
抗SESN1抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
western blot
Proteins
製品番号
詳細
Species
Sestrin 1 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥44% (SDS-PAGE),
Species
human