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Merck

SELPLG

selectin P ligand

別名:
CD162, CLA, PSGL-1, PSGL1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(20345) selectin, platelet (p-selectin) ligand
  • Rat(363930) selectin P ligand
  • cow(617434) selectin P ligand
  • sheep(101102589) selectin P ligand
  • naked mole-rat(101713908) selectin P ligand
  • domestic guinea pig(100712957) selectin P ligand
  • Zebrafish(100884146) selectin P ligand
  • chicken(772212) selectin P ligand
  • dog(611673) selectin P ligand
  • Horse(100034025) selectin P ligand
  • domestic cat(101087945) selectin P ligand

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ELISA

製品番号
詳細
Species
Human PSGL-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-PSGL-1/CD162 Antibody, clone KPL-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-P-Selectin Glycoprotein Ligand-1 Antibody, clone KPL-1, clone KPL-1, Chemicon®, from mouse,
交差性
human
アプリケーション
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-CD162-APC antibody produced in mouse, clone TC2,
交差性
アプリケーション
flow cytometry
Anti-SELPLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SELPLG,
Species
human
MISSION® esiRNA, targeting mouse Selplg,
Species
mouse