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Merck

SCN2A

sodium channel, voltage-gated, type II, alpha subunit

別名:
BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6326) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • chicken(395945) sodium channel, voltage-gated, type II, alpha subunit
  • dog(478773) sodium channel, voltage-gated, type II, alpha subunit
  • Horse(100051816) sodium channel, voltage-gated, type II, alpha subunit
  • domestic cat(101080472) sodium channel, voltage-gated, type II, alpha subunit
  • domestic guinea pig(100716680) sodium channel, voltage-gated, type II, alpha subunit
  • naked mole-rat(101715020) sodium channel, voltage-gated, type II, alpha subunit
  • cow(539718) sodium channel, voltage-gated, type II, alpha subunit
  • sheep(101103126) sodium channel, voltage-gated, type II, alpha subunit

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Small Molecule - Antagonist

製品番号
詳細
Species
リルゾール, solid,
Species
rat, human
Oxcarbazepine, ≥98% (HPLC), solid,
Species
rat, human
BIA 2-093, ≥98% (HPLC), solid,
Species
rat, human
リドカイン, powder,
Species
rat, human
ラモトリジン, ≥98%, powder,
Species
rat, human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-SCN2A Antibody, clone 5H10.2, clone 5H10.2, from mouse,
交差性
human
アプリケーション
western blot
Anti-SODIUM CHANNEL-PAN antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-Sodium Channel Antibody, Voltage Gated, Brain Type II, Chemicon®, from rabbit,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot
モノクロナール抗ナトリウムチャネル, Pan マウス宿主抗体, ~1 mg/mL, clone K58/35, purified immunoglobulin,
交差性
mammals
アプリケーション
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

製品番号
詳細
Species
リドカイン 塩酸塩 一水和物, solid,
Species
human
リドカイン 塩酸塩 一水和物, United States Pharmacopeia (USP) Reference Standard,
Species
human
リドカイン, United States Pharmacopeia (USP) Reference Standard,
Species
human
プロカイン 塩酸塩, ≥97%,
Species
human
プロカインアミド 塩酸塩, ≥98% (HPLC),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting mouse Scn2a,
Species
mouse
MISSION® esiRNA, targeting human SCN2A,
Species
human