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Merck

NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

別名:
CI-75Kd, CI-75k, PRO1304
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4719) Summary: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(227197) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • Rat(301458) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • Zebrafish(493605) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • cow(288380) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • Horse(100066330) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • domestic cat(101100747) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • dog(478880) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • chicken(424102) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • Goat(100861376) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • sheep(101115434) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101698993) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100726311) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Complex I-75kD Antibody, from rabbit, purified by affinity chromatography,
交差性
bovine, chimpanzee, human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗NDUFS1抗体 マウス宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
western blot
抗NDUFS1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
抗NDUFS1抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, canine, human, mouse, rat
アプリケーション
ELISA
western blot
抗NDUFS1抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
メトホルミン 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
1,1-ジメチルビグアニド 塩酸塩, 97%,
Species
human
メトホルミン 塩酸塩, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
1,1-ジメチルビグアニド 塩酸塩, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Ndufs1,
Species
mouse
MISSION® esiRNA, targeting human NDUFS1,
Species
human