MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
別名:
ACTFS, HDMX, hdm2
Species:
Human MDM2 (4193), Mouse Mdm2 (17246), Rat Mdm2 (314856), Zebrafish mdm2 (30637), dog MDM2 (403693), domestic cat MDM2 (493939), cow MDM2 (540378), Horse MDM2 (100033891), chicken MDM2 (395609), domestic guinea pig Mdm2 (100724684) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(4193) Summary: This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
- Mouse(17246) transformed mouse 3T3 cell double minute 2
- Rat(314856) p53 E3 ubiquitin protein ligase
- Zebrafish(30637) transformed 3T3 cell double minute 2 homolog (mouse)
- dog(403693) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- domestic cat(493939) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- cow(540378) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- Horse(100033891) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- chicken(395609) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
- domestic guinea pig(100724684) MDM2 oncogene, E3 ubiquitin protein ligase
- naked mole-rat(101724821) MDM2 oncogene, E3 ubiquitin protein ligase
- sheep(101104979) Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
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ELISA
製品番号
詳細
Species
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-MDM2 Antibody, clone 2A10, clone 2A10, from mouse,
交差性
human
アプリケーション
immunoprecipitation (IP)
western blot
western blot
モノクロナール抗MDM2 マウス宿主抗体, ~2 mg/mL, clone MD-219, purified immunoglobulin, buffered aqueous solution,
交差性
mouse
アプリケーション
ELISA
flow cytometry
immunocytochemistry
microarray
western blot
flow cytometry
immunocytochemistry
microarray
western blot
Anti-phospho-MDM2 (pSer166) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot