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Merck

LMNA

lamin A/C

別名:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
Species:
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), Zebrafish lmna (195815), cow LMNA (404144), Horse LMNA (100057663), domestic cat LMNA (101086199), dog LMNA (480124), chicken LMNA (415464), domestic guinea pig Lmna (100735212) ...詳細
UniProtKB ID:
P02545, B4DI32, D3DVB0, E7EUI9, P02546, Q5TCJ2, Q5TCJ3, Q969I8
遺伝子ID:
  • Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
  • Mouse(16905) lamin A
  • Rat(60374) lamin A/C
  • Zebrafish(195815) lamin A
  • cow(404144) lamin A/C
  • Horse(100057663) lamin A/C
  • domestic cat(101086199) lamin A/C
  • dog(480124) lamin A/C
  • chicken(415464) lamin A/C
  • domestic guinea pig(100735212) lamin A/C
  • naked mole-rat(101704567) lamin A/C
  • sheep(101107924) lamin A/C

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Antibodies

製品番号
詳細
交差性
アプリケーション
05-1231
Anti-Progerin Antibody, clone 13A4, clone 13A4, Upstate®, from mouse,
交差性
human
アプリケーション
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
MABT858
抗プレラミンA抗体、クローンPL-1C7, clone PL-1C7, from mouse,
交差性
human, mouse
アプリケーション
ELISA
flow cytometry
immunocytochemistry
western blot
SAB4200272
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
交差性
human
アプリケーション
immunofluorescence
immunoprecipitation (IP)
western blot
MABT345
抗プレラミンA抗体、クローン7G11, clone 7G11, from rat,
交差性
mouse
アプリケーション
immunofluorescence
western blot
MAB3540
Anti-Lamin A Antibody, CT, a.a. 598-611, clone 133A2, clone 133A2, Chemicon®, from mouse,
交差性
bovine, canine, human, mouse, rat
アプリケーション
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
EMU056191
MISSION® esiRNA, targeting mouse Lmna,
Species
mouse
EHU063791
MISSION® esiRNA, targeting human LMNA,
Species
human