LDLR
low density lipoprotein receptor
別名:
FH, FHC, LDLCQ2
Species:
Human LDLR (3949), Mouse Ldlr (16835), Rat Ldlr (300438), Zebrafish ldlr (387529), dog LDLR (100683160), chicken LDLR (395103), domestic cat LDLR (101080362), cow LDLR (281276), Domestic Rabbit LDLR (100009086), domestic guinea pig Ldlr (100724238)
UniProtKB ID:
遺伝子ID:
- Human(3949) Summary: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
- Mouse(16835) low density lipoprotein receptor
- Rat(300438) low density lipoprotein receptor
- Zebrafish(387529) low density lipoprotein receptor
- dog(100683160) low density lipoprotein receptor
- chicken(395103) low density lipoprotein receptor
- domestic cat(101080362) low density lipoprotein receptor
- cow(281276) low density lipoprotein receptor
- Domestic Rabbit(100009086) low density lipoprotein receptor
- domestic guinea pig(100724238) low density lipoprotein receptor
- naked mole-rat(101703463) low density lipoprotein receptor
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ELISA
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-Low Density Lipoprotein Antibody, copper oxidized, serum, Chemicon®,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗LDLR ウサギ宿主抗体, Ab1, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗LDL受容体抗体 クローン2N19 ZooMAb® ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, rat
アプリケーション
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-LDL Receptor Antibody, clone 2H7.1, clone 2H7.1, from mouse,
交差性
human
アプリケーション
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot