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Merck

IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

別名:
IMPD2, IMPDH-II
Species:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), Zebrafish impdh2 (317745), Horse IMPDH2 (100063255), cow IMPDH2 (511969), domestic cat IMPDH2 (101080693), chicken IMPDH2 (416058), dog IMPDH2 (476630), domestic guinea pig Impdh2 (100730768) ...詳細
UniProtKB ID:
P12268, Q6LEF3
遺伝子ID:
  • Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
  • Mouse(23918) inosine 5'-phosphate dehydrogenase 2
  • Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
  • Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
  • Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
HPA001400
抗IMPDH2抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
ST1578
Anti-IMPDH2 Mouse mAb (1E12-B6), liquid, clone 1E12-B6, Calbiochem®,
交差性
human
アプリケーション
WH0003615M1
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)
western blot
SAB1410715
抗IMPDH2抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
SAB1406037
抗IMPDH2抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
N4505
β-ニコチンアミドアデニンジヌクレオチド, 還元型 二カリウム塩, ,
Species
human
A4882
6-チオグアニン, ≥98%,
Species
human
M5255
ミコフェノール酸, ≥98%,
Species
human
R9644
リバビリン, antiviral,
Species
human
M3536
ミコフェノール酸, powder, BioReagent, suitable for cell culture,
Species
human

Proteins

製品番号
詳細
Species
I1782
イノシン一リン酸デヒドロゲナーゼ Type II ヒト, recombinant, expressed in E. coli,
Species
human

esiRNA

製品番号
詳細
Species
EHU027541
MISSION® esiRNA, targeting human IMPDH2,
Species
human
EMU094871
MISSION® esiRNA, targeting mouse Impdh2,
Species
mouse