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Merck

HIRA

histone cell cycle regulator

別名:
DGCR1, TUP1, TUPLE1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7290) Summary: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
  • Mouse(15260) histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Rat(363849) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Zebrafish(568076) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • fruit fly(31680) CG12153 gene product from transcript CG12153-RA
  • cow(511514) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Horse(100052845) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • domestic cat(101098170) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • dog(486424) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Thale Cress(823578) protein HIRA
  • chicken(374074) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • sheep(101120607) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Domestic Rabbit(100352472) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-HIRA Antibody, clone WC119, clone WC119, from mouse,
交差性
human, mouse
アプリケーション
immunoprecipitation (IP)
western blot
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗HIRA抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-HIRA (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
抗HIRA抗体 マウス宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human HIRA, C22ORF39,
Species
human
MISSION® esiRNA, targeting mouse Hira,
Species
mouse