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Merck

HEXA

hexosaminidase A (alpha polypeptide)

別名:
TSD
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3073) Summary: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009]
  • Mouse(15211) hexosaminidase A
  • Rat(300757) hexosaminidase A
  • Zebrafish(323613) hexosaminidase A (alpha polypeptide)
  • chicken(415320) hexosaminidase A (alpha polypeptide)
  • cow(504468) hexosaminidase A (alpha polypeptide)
  • Horse(100063584) hexosaminidase A (alpha polypeptide)
  • domestic cat(101091627) hexosaminidase A (alpha polypeptide)
  • dog(487633) hexosaminidase A (alpha polypeptide)
  • sheep(100145856) hexosaminidase A (alpha polypeptide)
  • Domestic Rabbit(100008950) hexosaminidase A (alpha polypeptide)
  • domestic guinea pig(100712955) hexosaminidase A (alpha polypeptide)
  • naked mole-rat(101718368) hexosaminidase A (alpha polypeptide)

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ELISA

Product Number
詳細
Species
Human HEXA ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
詳細
交差性
アプリケーション
Anti-HEXA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
Anti-HEXA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-HEXA (C-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit, sheep
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
詳細
Species
ケルセチン 3-β-D-グルコシド, ≥90% (HPLC),
Species
mouse
バイカリン, 95%,
Species
mouse
ケルセチン 3-D-ガラクトシド, ≥97.0% (HPLC),
Species
mouse
3-ヒドロキシフラボン, ≥98%,
Species
mouse
(±)-タキシホリン 水和物, ≥90% (HPLC),
Species
mouse

esiRNA

Product Number
詳細
Species
MISSION® esiRNA, targeting human HEXA,
Species
human