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Merck

GFI1

growth factor independent 1 transcription repressor

別名:
GFI-1, GFI1A, SCN2, ZNF163
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2672) Summary: This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14581) growth factor independent 1
  • Rat(24388) growth factor independent 1 transcription repressor
  • chicken(429088) growth factor independent 1 transcription repressor
  • domestic cat(100127020) growth factor independent 1 transcription repressor
  • cow(100139952) growth factor independent 1 transcription repressor
  • dog(490156) growth factor independent 1 transcription repressor
  • sheep(101116880) growth factor independent 1 transcription repressor
  • naked mole-rat(101715410) growth factor independent 1 transcription repressor
  • domestic guinea pig(100716876) growth factor independent 1 transcription repressor

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Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-GFI1 antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-GFI1 (AB2) antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, human, pig, rat
アプリケーション
western blot
Anti-Growth Factor Independence-1 antibody, Mouse monoclonal, clone 2.5D.17, purified from hybridoma cell culture,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
microarray

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GFI1,
Species
human