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Merck

CREBBP

CREB binding protein

別名:
CBP, KAT3A, RSTS
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1387) Summary: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
  • Mouse(12914) CREB binding protein
  • Rat(54244) CREB binding protein
  • Zebrafish(100535787) CREB binding protein
  • dog(479866) CREB binding protein
  • Horse(100069613) CREB binding protein
  • domestic cat(101094471) CREB binding protein
  • chicken(416667) CREB binding protein
  • cow(505453) CREB binding protein
  • naked mole-rat(101714025) CREB binding protein
  • domestic guinea pig(100716770) CREB binding protein
  • sheep(101123600) CREB binding protein

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗CREBBP抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-CREB-BP antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CBP Antibody, clone 3N20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, rat
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry
抗CBP抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-CREBBP antibody produced in mouse, clone 2B6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

Proteins

製品番号
詳細
Species
CBP (1319-1710)、GSTタグ融合 ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
KAT3A (518-1207)、GSTタグ融合 ヒト, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Crebbp,
Species
mouse
MISSION® esiRNA, targeting mouse Crebbp,
Species
mouse
MISSION® esiRNA, targeting human CREBBP,
Species
human