ALOX5
arachidonate 5-lipoxygenase
別名:
5-LO, 5-LOX, 5LPG, LOG5
Species:
Human ALOX5 (240), Mouse Alox5 (11689), Rat Alox5 (25290), Zebrafish alox5 (573013), chicken ALOX5 (423769), dog ALOX5 (477753), domestic cat ALOX5 (101097422), cow ALOX5 (404074), Horse ALOX5 (100062042), Zebrafish alox5 (567204) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(240) Summary: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- Mouse(11689) arachidonate 5-lipoxygenase
- Rat(25290) arachidonate 5-lipoxygenase
- Zebrafish(573013) arachidonate 5-lipoxygenase
- chicken(423769) arachidonate 5-lipoxygenase
- dog(477753) arachidonate 5-lipoxygenase
- domestic cat(101097422) arachidonate 5-lipoxygenase
- cow(404074) arachidonate 5-lipoxygenase
- Horse(100062042) arachidonate 5-lipoxygenase
- Zebrafish(567204) arachidonate 5-lipoxygenase
- domestic guinea pig(100718093) arachidonate 5-lipoxygenase
- naked mole-rat(101700210) arachidonate 5-lipoxygenase
- sheep(101117390) arachidonate 5-lipoxygenase
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗ALOX5抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
immunohistochemistry
抗ALOX5 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human, mouse
アプリケーション
immunofluorescence
western blot
western blot
抗5′-リポキシゲナーゼ抗体, Chemicon®, from rabbit,
交差性
human, mouse, rabbit, rat
アプリケーション
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Arachidonate 5 Lipoxygenase antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot