SML3832

Alnustone

≥98% (HPLC)

• Synonym(s): (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
• Empirical Formula (Hill Notation): C₁₉H₁₈O
• CAS Number: 33457-62-4
• Molecular Weight: 262.35
• MDL number: MFCD00926095
• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(CCc2ccccc2)\C=C\C=C\c1ccccc1
• InChI: 1S/C19H18O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-14H,15-16H2/b13-7+,14-8+
• InChI key: OWMJDOUOHDOUFG-FNCQTZNRSA-N

Description

Biochem/physiol Actions

Alnustone is a diarylheptanoid isolated from Alpinia katsumadai Hayata, rhizomes of Curcuma xanthorrhiza and other plants that exhibits anti-hyperglycemic, anti-inflammatory, antihepatotoxic and antiemetic activities. Alnustone is a potent inhibitor of the Thyroid Adenoma Associated (THADA) function, which reverses THADA-induced β-cell dysfunction and ameliorate hyperglycemia in obese mice. It significantly decreases fed blood glucose and improved glucose tolerance in mice.

Diarylheptanoid isolated from Alpinia katsumadai Hayata and other plants that exhibits anti-hyperglycemic, anti-inflammatory, antihepatotoxic and antiemetic activities

Caution

Hygroscopic

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable