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Safety Information

100277

Sigma-Aldrich

Adamantane

≥99%

Synonym(s):

Tricyclo[3.3.1.13,7]decane

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About This Item

Empirical Formula (Hill Notation):
C10H16
CAS Number:
281-23-2
Molecular Weight:
136.23
Beilstein:
1901173
EC Number:
206-001-4
MDL number:
MFCD00074719
UNSPSC Code:
12352100
PubChem Substance ID:
24846519
NACRES:
NA.22

Quality Level

100

Assay

≥99%

form

solid

mp

209-212 °C (subl.) (lit.)

SMILES string

C1[C@H]2C[C@H]3C[C@@H]1C[C@@H](C2)C3

InChI

1S/C10H16/c1-7-2-9-4-8(1)5-10(3-7)6-9/h7-10H,1-6H2/t7-,8+,9-,10+

InChI key

ORILYTVJVMAKLC-YNFQOJQRSA-N

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Application

Adamantane is the structural backbone of various medicinally important compounds such as amantadine, memantine, saxagliptin and vildagliptin. It is used in the synthesis of adamantine-based dirhodium tetracarboxylate catalyst for carbenoid reactions. It can also be used as a seeding material for the nucleation of nanocrystalline diamond films.

Hazard Statements

H413

Precautionary Statements

P273

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

100277-5G-KC:
100277-25G:
100277-100G:
100277-BULK:
100277-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN2374
MKCL1826
MKCK0000
MKCH5164
MKCF0706

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Nucleation enhancement of nanocrystalline diamond growth at low substrate temperatures by adamantane seeding.
Tsugawa K, et al.
The Journal of Physical Chemistry C, 114(9), 3822-3824 (2010)
Ayako Takahashi et al.
American journal of physiology. Heart and circulatory physiology, 304(10), H1361-H1369 (2013-03-19)
Incretin hormones, including glucagon-like peptide-1 (GLP-1), a target for diabetes mellitus (DM) treatment, are associated with cardioprotection. As dipeptidyl-peptidase IV (DPP-IV) inhibition increases plasma GLP-1 levels in vivo, we investigated the cardioprotective effects of the DPP-IV inhibitor vildagliptin in a
Benjamin M Scirica et al.
The New England journal of medicine, 369(14), 1317-1326 (2013-09-03)
The cardiovascular safety and efficacy of many current antihyperglycemic agents, including saxagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, are unclear. We randomly assigned 16,492 patients with type 2 diabetes who had a history of, or were at risk for, cardiovascular
Kenneth J Olejar et al.
Antioxidants (Basel, Switzerland), 8(7) (2019-07-25)
Valorization of agricultural waste has become increasingly important. Wastes generated by wineries are high in phenolic compounds with antioxidant and antibacterial properties, which contribute to phytotoxicity, making their immediate use for agricultural means limited. Utilizing a water-based extraction method, the
Louis H Miller et al.
Nature medicine, 19(2), 156-167 (2013-02-08)
Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan, claims the lives of nearly a million children each year in Africa alone and is a top public health concern. Evidence is accumulating that resistance to artemisinin derivatives, the
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Global Trade Item Number

SKUGTIN
100277-25G4061838661845
100277-100G4061838661838

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