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Safety Information

S7273

Sigma-Aldrich

Sera from mouse

frozen liquid (from clotted whole blood)

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

biological source

mouse

Quality Level

300

description

Contains no azides

sterility

sterile; aseptically filled

form

frozen liquid (from clotted whole blood)

origin

USA origin

shipped in

dry ice

storage temp.

−20°C

General description

Mouse serum is used in a variety of mouse cell culture systems to study viral infection, inhibition, and transduction processes.

Application

Sera from mouse has been used:
  • as a source of inter-α-inhibitor (IαI) in protein modification to form the heavy chain (HC)-hyaluronan (HA) complex
  • to culture primary mouse airway smooth muscle cells (MASM) and primary human airway smooth muscle cells (HASM)
  • as analytical quality control (QC) sample for metabolomics analysis of treated mice serum

Suitability

Not tested for use in cell culture

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

S7273-50ML-PW:
S7273-10ML:
S7273-BULK:
S7273-VAR:
S7273-50ML:
S7273PROC:
S7273-PH:
S7273-10ML-PW:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mark E Lauer et al.
The Journal of biological chemistry, 288(1), 205-214 (2012-11-21)
The covalent transfer of heavy chains (HCs) from inter-α-inhibitor (IαI) to hyaluronan (HA) via the protein product of tumor necrosis factor-stimulated gene-6 (TSG-6) forms the HC-HA complex, a pathological form of HA that promotes the adhesion of leukocytes to HA
Alexandra E Livanos et al.
Nature microbiology, 1(11), 16140-16140 (2016-10-27)
The early life microbiome plays important roles in host immunological and metabolic development. Because the incidence of type 1 diabetes (T1D) has been increasing substantially in recent decades, we hypothesized that early-life antibiotic use alters gut microbiota, which predisposes to
Sven-Bastiaan Haange et al.
Metabolites, 12(7) (2022-07-28)
Bile acids are a key mediator of the molecular microbiome-host interaction, and various mass spectrometry-based assays have been developed in the recent decade to quantify a wide range of bile acids. We compare existing methodologies to harmonize them. Methodology for
Mark E Lauer et al.
The Journal of biological chemistry, 284(8), 5313-5323 (2008-12-17)
The covalent association of inter-alpha-inhibitor-derived heavy chains (HCs) with hyaluronan was first described in synovial fluid from arthritic patients and later described as a structural and functional component of hyaluronan "cable" structures produced by many different cells and stimuli. HC
V Salucci et al.
Scandinavian journal of immunology, 62(3), 206-217 (2005-09-24)
Adenovirus vectors encoding carcinoembryonic antigen (Ad-CEA) or costimulatory molecules CD80, intercellular adhesion molecule-1 (ICAM-1) and leucocyte function-associated antigen-3 (LFA-3) (Ad-STIM) were used to transduce murine bone marrow-derived dendritic cells (BMDC). BMDC were characterized for expression of activation markers and for
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