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Safety Information

A3139

Sigma-Aldrich

Albumin from mouse serum

lyophilized powder, ≥96% (agarose gel electrophoresis)

Synonym(s):

Mouse albumin

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About This Item

CAS Number:
9048-46-8
EC Number:
232-936-2
MDL number:
MFCD00804573
UNSPSC Code:
12352202
NACRES:
NA.27

biological source

mouse

Quality Level

200

Assay

≥96% (agarose gel electrophoresis)

form

lyophilized powder

technique(s)

ELISA: suitable
electrophoresis: suitable

UniProt accession no.

P07724

storage temp.

2-8°C

Gene Information

mouse ... ALB(11657)

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General description

Mouse albumin gene is mapped to mouse chromosome 5. It codes for an albumin, which is the most prominent protein in the blood plasma. Albumin is produced by the mature liver. Mouse albumin gene promoter region includes minimum six binding sites (A to F) for specific DNA-binding proteins.

Application

Albumin from mouse serum has been used in labelling by probe 2 for the characterization of matrix metalloprotease-12 by one-dimensional electrophoresis. It has also been used for the preparation of calibrator and controls in enzyme-linked immunosorbent assay (ELISA).

Biochem/physiol Actions

Albumin facilitates the formation of cytoplasmic lipid droplets in pancreatic stellate cells and adipocyte differentiation of 3T3-L1 cells. In addition, it effectively regulates biological activity of adipogenic transcription factors, peroxisome proliferator-activated receptor (PPAR - γ ) and (CCAAT/enhancer binding protein (C/EBP).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

A3139-5MG:
A3139-10MG:
A3139-VAR:
A3139-BULK:
A3139-100MG:
A3139-50MG:

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Certificates of Analysis (COA)

Lot/Batch Number
0000292112
0000292109
0000292110
0000292110
0000292109

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Albumin expression is required for adipocyte differentiation of 3T3-L1 cells
Yoo W, et al.
Biochemical and biophysical research communications, 397(2), 170-175 (2010)
Detection of endogenous matrix metalloprotease-12 active form with a novel broad spectrum activity-based probe
Nury C, et al.
The Journal of biological chemistry, 288(8), 5636-5644 (2013)
Softened food reduces weight loss in the streptozotocin-induced male mouse model of diabetic nephropathy
Norgaard SA, et al.
Laboratory Animals, 52(4), 373-383 (2018)
Albumin-binding domain from Streptococcus zooepidemicus protein Zag as a novel strategy to improve the half-life of therapeutic proteins
Cantante C, et al.
Journal of Biotechnology, 253(6), 23-33 (2017)
Distant enhancers stimulate the albumin promoter through complex proximal binding sites
Vorachek WR, et al.
Test, 275(37), 29031-29041 (2000)
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