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Key Documents

Safety Information

P9275

Sigma-Aldrich

Plasma

from mouse

Synonym(s):

Citrated plasma

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About This Item

MDL number:
MFCD00131920
UNSPSC Code:
12352207
NACRES:
NA.71

biological source

mouse

Quality Level

200

form

powder

contains

0.8% sodium citrate as anticoagulant

storage temp.

2-8°C

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General description

Plasma is the liquid part of the blood and lymphatic fluid, which makes up about half of its volume. Plasma is devoid of cells and, unlike serum, has not clotted. Some of the more common proteins found in plasma are albumin and prealbumin, α1-acid glycoprotein, transferrin, lipoproteins (HDL, LDL, and VLDL), immunoglobulins, complement proteins, and coagulation proteins (thrombin, plasminogin, and fibrinogen). Citrated plasma contains citrate (0.8% sodium citrate) as an anticoagulant.

Plasma contains a variety of proteins with diverse functions. The primary functions of the plasma proteins include the maintenance of colloid osmotic pressure, pH, and electrolyte balance; the transport of metal ions, fatty acids, steroids, hormones, and drugs to various organs of the body; use as a source for amino acids for tissue nourishment; hemostasis and the prevention of thrombosis; the regulation of cellular activity and function through hormone signaling; and defense against invasion through the actions of antibodies and complement components.

Preparation Note

This product is prepared from pooled mouse blood. It contains 0.8% sodium citrate as an anticoagulant. It is prepared from whole blood that is collected with anticoagulants (9:1) and centrifuged to remove cells and cellular debris. It is tested for clotting, which indicates that the clotting factors in the product are active. However, it is not analyzed to determine whether other enzymes present are native or denatured. The resulting plasma is 0.45 microm filtered and lyophilized from the indicated volume.
Whole blood collected with anticoagulants (9:1), pooled, and centrifuged. The resulting plasma is 0.45 μm filtered and lyophilized from the indicated volumes.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

P9275-PH:
P9275-VAR:
P9275PROC:
P9275-BULK:
P9275-1ML:
P9275-1ML-PW:

Certificates of Analysis (COA)

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A I Potapovich et al.
British journal of pharmacology, 158(5), 1236-1247 (2009-09-30)
The immunomodulatory effects of alpha-fetoprotein (AFP) on lymphocytes and macrophages have been described in vitro and in vivo. Recombinant forms of human AFP have been proposed as potential therapeutic entities for the treatment of autoimmune diseases. We examined the effects

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