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Safety Information

D6277

Sigma-Aldrich

N-Decanoyl-N-methylglucamine

≥98% (GC)

Synonym(s):

N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10

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About This Item

Empirical Formula (Hill Notation):
C17H35NO6
CAS Number:
85261-20-7
Molecular Weight:
349.46
Beilstein:
6974359
MDL number:
MFCD00036801
UNSPSC Code:
12161900
PubChem Substance ID:
24894017
NACRES:
NA.25

description

non-ionic

Quality Level

200

Assay

≥98% (GC)

form

powder

mol wt

349.46 g/mol

technique(s)

ligand binding assay: suitable
protein purification: suitable

CMC

6-7 mM (20-25°C)

storage temp.

2-8°C

SMILES string

OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O

InChI

1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3

InChI key

UMWKZHPREXJQGR-UHFFFAOYSA-N

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General description

N-Decanoyl-N-methylglucamine is a nonionic detergent used in lysis buffers.

Application

N-Decanoyl-N-methylglucamine has been used in a study to assess the effect of surfactants on wetting behavior of super-hydrophobic surfaces. It has also been used in a study to investigate the clinical impact of Human metapneumovirus (hMPV) vaccines on Syrian golden hamsters.
Non-ionic, dialyzable detergent used for the solubilization of membrane proteins

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

D6277-1G:
D6277-500MG:
D6277-VAR:
D6277-BULK:
D6277-5G:
D6277-25G:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ2128
SLBZ0434
SLBW6851
SLBR7848V
SLBL2721V

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Optimal concentrations of N-decanoyl-N-methylglucamine and sodium dodecyl sulfate allow the extraction and analysis of membrane proteins
Chuang, J., et al.
Analytical Biochemistry, 418, 3-3 (2011)
Khemraj Budachetri et al.
mBio, 11(4) (2020-07-30)
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. E. chaffeensis outer membrane protein entry triggering protein of Ehrlichia (EtpE) is necessary for bacterial entry into
Sander Herfst et al.
The Journal of general virology, 88(Pt 10), 2702-2709 (2007-09-18)
Human metapneumovirus (hMPV), a newly discovered paramyxovirus, is associated with acute respiratory-tract illness, primarily in young children, individuals with underlying disease and the elderly. Two genetic lineages of hMPV circulate around the world, and viruses from these two lineages demonstrate
R C Poole et al.
The Biochemical journal, 283 ( Pt 3), 855-862 (1992-05-01)
1. Intact erythrocytes were incubated with 100 microM-4,4'-di-isothiocyanostilbene-2,2'-disulphonate (DIDS), a concentration sufficient to inhibit lactate transport irreversibly by 65%. DIDS-labelled proteins were detected by immunoblotting of erythrocyte membrane proteins with an anti-DIDS antibody. Labelled polypeptides of 35-45 kDa in rat
R Mohammadi et al.
Langmuir : the ACS journal of surfaces and colloids, 20(22), 9657-9662 (2004-10-20)
The effect of surfactants on wetting behavior of super-hydrophobic surfaces was investigated. Super-hydrophobic surfaces were prepared of alkylketene dimer (AKD) by casting the AKD melt in a specially designed mold. Time-dependent studies were carried out, using the axisymmetric drop shape
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