C8667
Cholesterol
Sigma Grade, ≥99%
Synonym(s):
3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
About This Item
Recommended Products
biological source
sheep wool
Quality Level
grade
Sigma Grade
Assay
≥99%
form
powder
bp
360 °C (lit.)
mp
147-149 °C (lit.)
solubility
water: soluble 0.00003 g/L at 20 °C
density
1.067 g/mL at 25 °C (lit.)
shipped in
ambient
storage temp.
−20°C
SMILES string
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key
HVYWMOMLDIMFJA-DPAQBDIFSA-N
Gene Information
human ... POLA1(5422) , TOP2A(7153)
rat ... Ar(24208) , Polb(29240)
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Related Categories
Application
Biochem/physiol Actions
Preparation Note
also commonly purchased with this product
related product
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Regulatory Listings
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JAN Code
C8667-500MG:
C8667-5G:
C8667-BULK:
C8667-1G:
2003140:
C8667-100G:
C8667-VAR:
C8667-25G:
2530047:
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Articles
Biosynthesis of cholesterol generally takes place in the endoplasmic reticulum of hepatic cells and begins with acetyl- CoA, which is mainly derived from an oxidation reaction in the mitochondria. Acetyl-CoA and acetoacetyl-CoA are converted to 3-hydroxy- 3-methylglutaryl-CoA (HMG-CoA) by HMG-CoA synthase.
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