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Key Documents

Safety Information

C3821

Sigma-Aldrich

Citrate-dextrose solution (ACD)

sterile-filtered

Synonym(s):

Acid citrate-dextrose, Anticoagulant citrate-dextrose

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About This Item

CAS Number:
8013-89-6
MDL number:
MFCD00212913
UNSPSC Code:
12161700
NACRES:
NA.25

sterility

sterile-filtered

Quality Level

200

form

liquid

pH

4.5-5.5

storage temp.

2-8°C

Related Categories

General description

Citrate-dextrose solution (ACD) is an anticoagulant and preservative used routinely for blood storage. The ideal red blood cells shelf life is 21 days when stored in ACD solution. Red blood cells in ACD solution utilize glucose and their viability is impairs when reinfused.

Application

Citrate-dextrose solution (ACD) has been used for dilution of blood for haematological studies. It has also been used as an anticoagulant during blood collection by cardiac puncture from mice and human bone marrow isolation.
For research use only. Not for use in diagnostic procedures.

Biochem/physiol Actions

Useful for anticoagulation of whole blood; erythrocyte survival

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Product No.
Description
Pricing

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C3821-50ML-PW:
C3821-10X50ML:
C3821-PH:
C3821-VAR:
C3821-BULK:
C3821PROC:
C3821-50ML:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Isolation, expansion and characterisation of mesenchymal stem cells from human bone marrow, adipose tissue, umbilical cord blood and matrix: a comparative study
Secunda R, et al.
Cytotechnology, 67(5), 793-807 (2015)
Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo
Katz SG, et al.
Molecular and Cellular Biology, 22(9), 3121-3128 (2002)
Mingming Yang et al.
Experimental and therapeutic medicine, 20(2), 1253-1260 (2020-08-09)
The p53 gene is well known as a key tumor suppressor gene; it is vital for hematopoietic stem cell differentiation and growth. In the present study, the change of platelets (PLTs) in p53 knockout mice (p53-/- mice) was investigated. The
Hideki Miyachi et al.
International journal of cardiology, 266, 61-66 (2018-06-12)
Acute thrombosis is a crucial cause of bioresorbable vascular graft (BVG) failure. Bone marrow-derived mononuclear cell (BM-MNC)-seeded BVGs demonstrated high graft patency, however, the effect of seeded BM-MNCs against thrombosis remains to be elucidated. Thus, we evaluated an antithrombotic effect
The storage of hard-packed red blood cells in citrate-phosphate-dextrose (CPD) and CPD-adenine (CPDA-1)
Beutler E and West C
Blood, 54(1), 280-284 (1979)
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