28266

Levofloxacin

98.0-102.0% anhydrous basis (HPLC)

• Synonym(s): (−)-Ofloxacin
• Empirical Formula (Hill Notation): C₁₈H₂₀FN₃O₄
• CAS Number: 100986-85-4
• Molecular Weight: 361.37
• Beilstein: 7327015
• MDL number: MFCD00865049
• PubChem Substance ID: 57648297
• NACRES: NA.85

Properties

• biological source: synthetic
• Quality Level: 200
• assay: 98.0-102.0% anhydrous basis (HPLC)
• form: powder or crystals
• color: light yellow-white to yellow-white
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: enzyme | inhibits
• SMILES string: OC(C(C1=O)=CN2C(C1=CC(F)=C3N4CCN(C)CC4)=C3OC[C@@H]2C)=O
• InChI: 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
• InChI key: GSDSWSVVBLHKDQ-JTQLQIEISA-N
• Gene Information: human ... KCNH1(3756)

Description

Application

Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Antibiotic against bacterial respiratory tract infections.

Biochem/physiol Actions

Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, thereby inhibiting cell division.

Packaging

10mg, 1g, 10g

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 28266.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H317 - H334
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1A - Skin Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves