Merck
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455180

Sigma-Aldrich

Hydrogen chloride solution

2.0 M in diethyl ether

Empirical Formula (Hill Notation):
HCl
CAS Number:
Molecular Weight:
36.46
MDL number:
PubChem Substance ID:
NACRES:
NA.21

form

liquid

Quality Level

concentration

1.90-2.20 M (with NaOH, titration)
2.0 M in diethyl ether

bp

34.6 °C

density

0.747 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

Cl

InChI

1S/ClH/h1H

InChI key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

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This Item
34554729483790964
Hydrogen chloride solution 3 M in methanol, for GC derivatization, LiChropur™

Supelco

90964

Hydrogen chloride solution

form

liquid

form

liquid

form

liquid

form

liquid

concentration

1.90-2.20 M (with NaOH, titration), 2.0 M in diethyl ether

concentration

3.80-4.40 M (by NaOH, titration), 4.0 M in dioxane

concentration

0.95-1.10 M (with NaOH, titration), 1.0 M in diethyl ether

concentration

3 M in methanol

bp

34.6 °C

bp

-

bp

-

bp

-

density

0.747 g/mL at 25 °C

density

1.05 g/mL at 25 °C

density

0.731 g/mL at 25 °C

density

0.871-0.881 g/mL at 20 °C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

General description

The product is a 2M solution of hydrogen chloride in diethyl ether.

Application

Hydrogen chloride solution can be used as a reagent to synthesize:
  • Cyanohydrin alkyl ethers via chiral Bronsted acid-mediated hydrocyanation of vinyl ethers with silyl cyanides.
  • N, N-Dimethylaniline hydrochloride salts via Pd-catalyzed Buchwald-Hartwig amination of aryl triflates with dimethylamines.
It can also be used as a catalyst for the amidation of carboxylic acids with amines to synthesize amides.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 1 - Met. Corr. 1 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-29.2 °F - closed cup

Flash Point(C)

-34 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

FSL

Flammable liquids
Special flammables
Hazardous rank I

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

455180-100ML:4.548173153742E12
455180-800ML:4.548173153759E12


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