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32995

Supelco

Levothyroxine sodium hydrate

PESTANAL®, analytical standard

Synonym(s):

3,3′,5,5′-Tetraiodo-L-thyronine monosodium salt hydrate, L-Thyroxin monosodium salt hydrate, Sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine hydrate

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About This Item

Empirical Formula (Hill Notation):
C15H10I4NNaO4 · xH2O
CAS Number:
25416-65-3
Molecular Weight:
798.85 (anhydrous basis)
EC Number:
200-221-4
MDL number:
MFCD06408007
UNSPSC Code:
41116107
PubChem Substance ID:
329754429

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1

InChI key

ANMYAHDLKVNJJO-LTCKWSDVSA-M

Gene Information

human ... THRA(7067) , THRB(7068)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

32995-25MG:4.548173997131E12

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ7843
SZBE017XV
SZBA082XV
SZE8323X
SZBA082X

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Mazen Lee Hamad et al.
Pharmaceutical development and technology, 20(3), 314-319 (2013-12-04)
Levothyroxine sodium is an important medication used primarily for treating patients with hypothyroidism. Levothyroxine sodium tablets have been recalled many times since their 1955 introduction to the US market. These recalls resulted from the failure of lots to meet their

Protocols

HPLC Analysis of Levothyroxine and Liothyronine on Ascentis® Express ES-Cyano

HPLC Analysis of Levothyroxine and Liothyronine on Ascentis® Express ES-Cyano

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