Merck
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487090

Sigma-Aldrich

Water-18O

99 atom % 18O

Synonym(s):
18O Labeled water
Linear Formula:
H218O
CAS Number:
Molecular Weight:
20.02
MDL number:
PubChem Substance ID:

Quality Level

description

Normalized with respect to hydrogen

isotopic purity

99 atom % 18O

bp

100 °C (lit.)

mp

0 °C (lit.)

density

1.11 g/mL at 20 °C (lit.)

mass shift

M+2

SMILES string

[18OH2]

InChI

1S/H2O/h1H2/i1+2

InChI key

XLYOFNOQVPJJNP-NJFSPNSNSA-N

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General description

H2180 is isotopically modified compound consisting of two hydrogen atoms covalently bonded to oxygen-18. It is most convenient to store, transport and use Oxygen-18 in the form of water enriched with this isotope.

Application

O-18 enriched water is used in Positron-Emission Tomography (PET), a nuclear imaging technique that is used to observe metabolic processes in the body as an aid to the diagnosis of disease such as tumors, staging of cancer, metastasis, dementia, etc. H2180 is currently the only potential universal bacterial substrate suitable for stable isotope probing (SIP). It has been used in the quantification of population-specific growth dynamics in benthic bacterial communities in response to changing redox conditions.

Packaging

1 g in serum bottle

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Ömer K Coskun et al.
The ISME journal, 13(6), 1546-1559 (2019-02-21)
The benthos in estuarine environments often experiences periods of regularly occurring hypoxic and anoxic conditions, dramatically impacting biogeochemical cycles. How oxygen depletion affects the growth of specific uncultivated microbial populations within these diverse benthic communities, however, remains poorly understood. Here
Elizabeth A Rettedal et al.
MicrobiologyOpen, 4(2), 208-219 (2015-02-05)
Current limitations in culture-based methods have lead to a reliance on culture-independent approaches, based principally on the comparative analysis of primary semantides such as ribosomal gene sequences. DNA can be remarkably stable in some environments, so its presence does not
H H Coenen et al.
Nuclear medicine and biology, 37(7), 727-740 (2010-09-28)
Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide thanks to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals. There is an armamentarium of fluorine-18 ((18)F) tracers that can be used for

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