(for PET), 97 atom % 18O

18O Water
Linear Formula:
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:


Normalized with respect to hydrogen

Quality Level

isotopic purity

97 atom % 18O


PET imaging: suitable


100 °C (lit.)


0 °C (lit.)


1.11 g/mL at 20 °C (lit.)


(for PET)

mass shift


SMILES string




InChI key


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Water-18O is an isotopically modified water, which is appropriate for PET applications.
It can also be used:
  • In paleoclimatology, hydrology, and plant ecology to determine soil stable oxygen isotope analysis of plant cellulose using δ18O.
  • To determine the diffusion of moisture into crystals using secondary ion mass spectrometry (SIMS).


250 mg in serum bottle
1 g in serum bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service,.
Packaged in septum-sealed serum bottles.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Diffusion of Water Species in Yttria-Stabilized Zirconia
Duong T, et al.
Journal of the American Chemical Society, 92(11), 2731-2737 (2009)
Xueyan Cao et al.
Food chemistry, 276, 266-273 (2018-11-10)
Milk glycoproteins are crucial nutrients with a variety of functions. However, whey N-glycoproteomes in human and bovine milks have not been characterized during lactation. Herein, using lectin enrichment and liquid chromatography tandem mass spectrometry, 68, 58, 100, and 98 N-glycoproteins...
Separating soil and leaf water 18O isotopic signals in plant stem cellulose
Sternberg, Leonel da Silveira Lobo and Anderson, William T and Morrison, Kanema
Geochimica et Cosmochimica Acta, 67(14), 2561-2566 (2003)
Qingfei Zheng et al.
Nature communications, 11(1), 3241-3241 (2020-06-28)
Protein arginine deiminase 4 (PAD4) facilitates the post-translational citrullination of the core histones H3 and H4. While the precise epigenetic function of this modification has not been resolved, it has been shown to associate with general chromatin decompaction and compete...
Natalia A Cherepanova et al.
The Journal of cell biology, 218(8), 2782-2796 (2019-07-13)
Human cells express two oligosaccharyltransferase complexes (STT3A and STT3B) with partially overlapping functions. The STT3A complex interacts directly with the protein translocation channel to mediate cotranslational glycosylation, while the STT3B complex can catalyze posttranslocational glycosylation. We used a quantitative glycoproteomics...
By first labeling molecular oxygen and then body water with 18O in a rat, Lifson measured the 18O abundance in expired CO2 and found the oxygens in CO2 exchanged with the oxygen in water. Indeed, these two oxygen containing species were in rapid isotopic equilibrium due to the actions of what we now know is carbonic anhydrase (Lifson, 1966)
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