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Key Documents

Safety Information

154563

Sigma-Aldrich

Tris Base

≥99.9%, solid, ultrapure grade

Synonym(s):

Tris Base, Tris(hydroxymethyl)aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

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About This Item

Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein:
741883
EC Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:

product name

Tris(hydroxymethyl)aminomethane, ultrapure grade, ≥99.9%

grade

ultrapure grade

Assay

≥99.9%

form

solid

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

solubility

water: 0.66 g/mL, clear, colorless

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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Application

Buffer and primary pH standard. pKa=8.3 at 20°C. Auxiliary material in pharmaceutical science.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

154563-BULK:
154563-VAR:
154563-1KG:
154563-500G:
154563-100G:
154563-5G:
154563-5KG:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chimica Oggi, 12, 24-24 (1994)
Chem. Abstr., 121, 212675r-212675r (1994)
Aldrichimica Acta, 16, 35-35 (1983)
Sylvain Clède et al.
Chemical communications (Cambridge, England), 48(62), 7729-7731 (2012-06-29)
A rhenium tris-carbonyl derivative has been designed to couple infrared and luminescent detection in cells. Both spectroscopies are consistent with one another; they point out the reliability of the present SCoMPI (for Single Core Multimodal Probe for Imaging) for bimodal
Corey A Baron et al.
Magnetic resonance in medicine, 73(3), 1075-1084 (2014-04-12)
An acquisition method that does not increase scan time or specific absorption rate is investigated for reducing the deleterious effects of cerebrospinal fluid (CSF) partial volume effects on diffusion tensor imaging (DTI) tractography. It is based on using a shorter

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