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Safety Information

T6687

Sigma-Aldrich

Tris Base

99-101% dry basis, crystalline, meets USP testing specifications

Synonym(s):

2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol, Tris

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About This Item

Empirical Formula (Hill Notation):
C4H11NO3
CAS Number:
77-86-1
Molecular Weight:
121.14
EC Number:
201-064-4
MDL number:
MFCD00004679
UNSPSC Code:
12352104
PubChem Substance ID:
24900399
NACRES:
NA.25

product name

Tromethamine, meets USP testing specifications

Agency

meets USP testing specifications

Quality Level

200

Assay

99-101% dry basis

form

crystalline

pH

10.0-11.5 (5%)

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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Application


  • Preparation and Characterization of a Rifampicin Coamorphous Material with Tromethamine Coformer: An Experimental-Theoretical Study.: This research explores the preparation and characterization of a coamorphous material of rifampicin with Tromethamine, showcasing its potential in enhancing the solubility and stability of pharmaceuticals (Queiroz et al., 2024).

  • REKOVER study protocol: a prospective patient treatment registry of tramadol and dexKetoprofen trometamol oral fixed-dose combination (SKUDEXA) in moderate to severe acute pain in real-world setting in Asia.: This study involves the use of dexketoprofen trometamol in a fixed-dose combination with tramadol for managing moderate to severe acute pain, providing evidence of its effectiveness in real-world clinical settings (Ho et al., 2024).

Other Notes

Easily compare specifications for Trizma products with the Trizma specification table.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T6687-1KG:
T6687-CH:
T6687-10KG:
T6687-BULK:
2550049:
T6687-5KG:
T6687-VAR:
T6687-100G:
T6687-25KG:
2550122:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sylvain Clède et al.
Chemical communications (Cambridge, England), 48(62), 7729-7731 (2012-06-29)
A rhenium tris-carbonyl derivative has been designed to couple infrared and luminescent detection in cells. Both spectroscopies are consistent with one another; they point out the reliability of the present SCoMPI (for Single Core Multimodal Probe for Imaging) for bimodal
Corey A Baron et al.
Magnetic resonance in medicine, 73(3), 1075-1084 (2014-04-12)
An acquisition method that does not increase scan time or specific absorption rate is investigated for reducing the deleterious effects of cerebrospinal fluid (CSF) partial volume effects on diffusion tensor imaging (DTI) tractography. It is based on using a shorter
Filippo Bertoli et al.
Small (Weinheim an der Bergstrasse, Germany), 10(16), 3307-3315 (2014-04-17)
Nanoparticles in contact with cells and living organisms generate quite novel interactions at the interface between the nanoparticle surface and the surrounding biological environment. However, a detailed time resolved molecular level description of the evolving interactions as nanoparticles are internalized
D R Brocks et al.
Clinical pharmacokinetics, 23(6), 415-427 (1992-12-01)
Ketorolac is a new chiral nonsteroidal anti-inflammatory drug (NSAID) which is marketed for analgesia as the racemate. The drug is administered as the water soluble tromethamine salt and is available in tablets or as an intramuscular injection. The absorption of
Jihane Homman-Ludiye et al.
Cerebral cortex (New York, N.Y. : 1991), 24(11), 2884-2898 (2013-05-28)
The visual cortex is organized into discrete domains characterized by their specific function, connectivity, chemoarchitecture, and cytoarchitecture. Gradients of transcription factors across the anteroposterior and mediolateral axes of the neocortex have previously been demonstrated to specify the main sensory regions.
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