1453049

Naloxone Related Compound D CII

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: (4R, 4aS, 7aR, 12bS)-3-allyl-4a,9-dihydroxy-2,3,4,4a-tetrahydro-1H,4,12- methanobenzofuro[3,2-e]-isoquinolin-7(7aH)-one
• Formula empirica (notazione di Hill): C₁₉H₁₉NO₄
• Numero CAS: 26451-92-3
• Peso molecolare: 325.36
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Famiglia di API: naloxone
• Confezionamento: pkg of 25 mg
• Produttore/marchio commerciale: USP
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C

Descrizione

Descrizione generale

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Applicazioni

• Interactive effects of opioid and adrenergic-α2 receptor agonists: Research highlights the complex interactions between µ-opioid and adrenergic-α2 receptor agonists in rats, focusing on the primary Kratom alkaloid Mitragynine and its metabolite 7-Hydroxymitragynine. This study is pivotal for understanding the biochemical pathways involved in opioid receptor antagonist research, offering insights into naloxone-related compound applications in opioid addiction and withdrawal management (Hiranita et al., 2022).


• Diels-Alder reactions of morphinan derivatives: The synthesis and transformations of Diels-Alder adducts of morphinan-6,8-dienes are discussed, illuminating the role of naloxone analogs in synthesizing novel opioid receptor antagonists. These findings contribute to the opioid antagonist research, particularly in exploring structural analogs of naloxone for enhanced therapeutic effects (Marton et al., 2022).


• Impact of brain metastases on methylnaltrexone: A post hoc analysis of three randomized studies investigates the influence of brain metastases on the CNS effects of methylnaltrexone. This research underlines the importance of naloxone derivatives in modifying opioid-induced side effects, which is crucial for the development of safer opioid antagonists in supportive cancer care (Brenner et al., 2021).

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable