1019428

Amifostine thiol

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: WR-1065, 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride, WR-1065 dihydrochloride
• Formula empirica (notazione di Hill): C₅H₁₄N₂S · 2HCl
• Numero CAS: 14653-77-1
• Peso molecolare: 207.16
• Numero MDL: MFCD00460339
• Codice UNSPSC: 41116107
• ID PubChem: 329748973
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: amifostine
• Produttore/marchio commerciale: USP
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: −20°C
• Stringa SMILE: Cl.Cl.NCCCNCCS
• InChI: 1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H; XDRLRDHLCIFZIW-UHFFFAOYSA-N

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Amifostine thiol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Amifostine
• Amifostine for Injection

Azioni biochim/fisiol

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H318
• Consigli di prudenza: P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
• Classi di pericolo: Acute Tox. 4 Oral - Eye Dam. 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable