PHL82571

Isosilybin B

phyproof^® Reference Substance

• Sinonimo/i: (2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone
• Formula empirica (notazione di Hill): C₂₅H₂₂O₁₀
• Numero CAS: 142796-22-3
• Peso molecolare: 482.44
• Numero MDL: MFCD18783097
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: primary reference standard
• Nome Commerciale: phyproof^® Reference Substance
• Saggio: ≥80.0% (HPLC)
• Forma fisica: solid
• Produttore/marchio commerciale: PhytoLab
• Stringa SMILE: COc1cc(ccc1O)[C@@H]2Oc3ccc(cc3O[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O
• InChI: 1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-18-7-12(3-5-16(18)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25+/m0/s1; FDQAOULAVFHKBX-WAABAYLZSA-N

Descrizione

Descrizione generale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Applicazioni

• Isosilybin B for hepatoprotective studies: Research elucidates how Isosilybin B regulates lipogenesis and fatty acid oxidation through the AMPK/SREBP-1c/PPARα pathway, offering insights into its potential as a hepatoprotective compound and its application in liver health studies (Liu et al., 2022).


• Isosilybin B in anticancer research: The study discusses the development of a topical formulation containing silymarin complex, including Isosilybin B, highlighting its skin permeability and potential in cancer prevention through dermal application (Shankar et al., 2023).


• Isosilybin B in antioxidant research: A study explores the antiviral efficacy of natural phytochemicals including Isosilybin B against the SARS-CoV-2 spike glycoprotein, emphasizing its role in antioxidant biochemistry and potential therapeutic applications (Aloufi et al., 2022).

Altre note

This compound is commonly found in plants of the genus: silybum

Note legali

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable