U3003

Uridine

powder, BioReagent, suitable for cell culture

• Sinonimo/i: 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• Formula empirica (notazione di Hill): C₉H₁₂N₂O₆
• Numero CAS: 58-96-8
• Peso molecolare: 244.20
• Beilstein: 754902
• Numero CE: 200-407-5
• Numero MDL: MFCD00006526
• Codice UNSPSC: 12352207
• ID PubChem: 24900638
• NACRES: NA.75

Proprietà

• Origine biologica: synthetic (organic)
• Nome Commerciale: BioReagent
• Saggio: ≥99%
• Forma fisica: powder
• tecniche: cell culture | mammalian: suitable
• Punto di fusione: 163-167 °C (lit.)
• Solubilità: H₂O: 50 mg/mL
• Stringa SMILE: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1; DRTQHJPVMGBUCF-XVFCMESISA-N
• Informazioni sul gene: mouse ... Uck1(22245)

Descrizione

Descrizione generale

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is a substrate for nucleotide synthesis in living organisms by de- novo and salvage pathways.

Applicazioni

Uridine has been used:

• as an inhibitor of schwann cell proliferation in rat dorsal root ganglia (DRG) neurons culture
• as a medium supplement for epiblasts culture
• as a component of 5-fluoro-2′-deoxyuridine stock solution used for neuronal culture

Azioni biochim/fisiol

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like, treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine induces insulin resistance.

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)