U2625

Uric acid

≥99%, crystalline

• Sinonimo/i: 2,6,8-Trihydroxypurine
• Formula empirica (notazione di Hill): C₅H₄N₄O₃
• Numero CAS: 69-93-2
• Peso molecolare: 168.11
• Beilstein: 156158
• Numero CE: 200-720-7
• Numero MDL: MFCD00005712
• Codice UNSPSC: 12352005
• ID PubChem: 24900634
• NACRES: NA.55

Proprietà

• Saggio: ≥99%
• Forma fisica: crystalline
• Punto di fusione: >300 °C (lit.)
• Stringa SMILE: O=C1NC(=O)C2=C(N1)NC(=O)N2
• InChI: 1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12); LEHOTFFKMJEONL-UHFFFAOYSA-N

Descrizione

Applicazioni

Uric acid has been used:

• in inducing hyperuricemia in mice
• as a component of digestion fluid for the simulation of in vitro human digestion model
• in selectivity test of the glucose sensor in sweat-based diabetes monitoring

Azioni biochim/fisiol

Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure. Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease. Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality. High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)