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Merck
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Key Documents

Altri documenti

T7313

Sigma-Aldrich

1-[2-(Trifluoromethyl)phenyl]imidazole

Sinonimo/i:

TRIM

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About This Item

Formula empirica (notazione di Hill):
C10H7F3N2
Numero CAS:
25371-96-4
Peso molecolare:
212.17
Numero MDL:
MFCD00041206
Codice UNSPSC:
12352202
ID PubChem:
24278754
NACRES:
NA.77

Origine biologica

synthetic (organic)

Livello qualitativo

200

Saggio

≥98% (GC)

Forma fisica

solid

Solubilità

DMSO: soluble 30 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

FC(F)(F)c1ccccc1-n2ccnc2

InChI

1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H
WZBWBNCQUTXYEL-UHFFFAOYSA-N

Informazioni sul gene

human ... NOS1(4842) , NOS2(4843) , NOS2B(201288) , NOS2C(645740) , NOS3(4846)

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Azioni biochim/fisiol

Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Yves Basset et al.
Ecology and evolution, 7(23), 9991-10004 (2017-12-15)
We have little knowledge of the response of invertebrate assemblages to climate change in tropical ecosystems, and few studies have compiled long-term data on invertebrates from tropical rainforests. We provide an updated list of the 72 species of Saturniidae moths
Juan Traba et al.
Scientific reports, 9(1), 9473-9473 (2019-07-03)
Farmland bird populations have strongly declined across Europe over the last decades due to agriculture intensification, despite successive reforms of EU's Common Agricultural Policy (CAP). In parallel, CAP has led to a reduction of fallow land, a critical habitat for
Yong Lin et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6023-6034 (2019-02-12)
Hepatitis B virus (HBV) replication and envelopment is dependent on cellular autophagy. Previously, we have provided evidence for the extensive lysosomal degradation of HBV virions and the hepatitis B surface antigen (HBsAg), which is likely controlled by autophagosome-lysosome fusion. Synaptosomal-associated
Amélie Wallenhammar et al.
PloS one, 12(7), e0181551-e0181551 (2017-07-29)
Tripartite motif-containing (TRIM) proteins are defined by the sequential arrangement of RING, B-box and coiled-coil domains (RBCC), where the B-box domain is a unique feature of the TRIM protein family. TRIM21 is an E3 ubiquitin-protein ligase implicated in innate immune
Jose A Adams et al.
Resuscitation, 74(3), 516-525 (2007-05-01)
Nitric oxide (NO) is a critical regulator of vascular tone, and signal transduction. NO is produced via three unique synthases (NOS); endothelial (eNOS), and neuronal (nNOS) are both constitutively expressed and inducible (iNOS) produced primarily after stimulation. NO has been
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