T7004

Thymidine 5′-monophosphate disodium salt hydrate

≥99%

• Sinonimo/i: 5′-Thymidylic acid disodium salt, TMP, dTMP
• Formula empirica (notazione di Hill): C₁₀H₁₃N₂Na₂O₈P · xH₂O
• Numero CAS: 33430-62-5
• Peso molecolare: 366.17 (anhydrous basis)
• Beilstein: 4086927
• Numero CE: 251-518-0
• Numero MDL: MFCD09039259
• Codice UNSPSC: 41106305
• ID PubChem: 329826857
• NACRES: NA.51

Proprietà

• Livello qualitativo: 200
• Saggio: ≥99%
• Temperatura di conservazione: −20°C
• Stringa SMILE: O.[Na+].[Na+].CC1=CN([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)C(=O)NC1=O
• InChI: 1S/C10H15N2O8P.2Na.H2O/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t6-,7+,8+;;;/m0.../s1; KCOPAVKVHIWPKB-SPSULGLQSA-L

Descrizione

Descrizione generale

Thymidine 5′-monophosphate de novo synthesis from deoxyuridine monophosphate (dUMP) is catalyzed by the enzyme thymidylate synthase.

Applicazioni

Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard for the quantification of metabolites from plasma and tumor interstitial fluid using liquid chromatography-mass spectrometry analysis (LC/MS). It has also been used as a single deoxy-mononucleotide to test its effect on the cell growth of human malignant intestinal CaCo-2 cells and normal rat intestinal cell line IEC-6 cells.

Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard solution.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)