SRP6159
FGF-basic human
recombinant, expressed in human cells, ≥95% (SDS-PAGE)
Sinonimo/i:
FGF-2, FGF-b, HBGF-2, HBGH-2, Prostatropin
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About This Item
Prodotti consigliati
Origine biologica
human
Ricombinante
expressed in human cells
Saggio
≥95% (SDS-PAGE)
Stato
lyophilized
PM
17 kDa (monomer, non-glycosylated)
Confezionamento
pkg of 10 μg
tecniche
cell culture | mammalian: suitable
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
Informazioni sul gene
human ... FGF2(2247)
Descrizione generale
FGF-basic is a member of the fibroblast growth factor (FGF) family. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. The gene encoding this protein is localized on human chromosome 4q28.
Azioni biochim/fisiol
FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. The protein associates with fibroblast growth factor receptors 1, 2 and 3 (FGFR-1, -2, -3).
Stato fisico
Lyophilized from a PBS solution.
Nota sulla preparazione
Centrifuge the vial prior to opening.
Ricostituzione
Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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