F5392
Fibroblast Growth Factor-Basic from bovine pituitary
~90% (SDS-PAGE and N-terminal analysis), lyophilized powder, suitable for cell culture
Sinonimo/i:
FGF2, bFGF
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About This Item
Prodotti consigliati
Nome del prodotto
Fibroblast Growth Factor-Basic from bovine pituitary, FGF-Basic, suitable for cell culture
Origine biologica
bovine pituitary glands
Livello qualitativo
Saggio
~90% (SDS-PAGE and N-terminal analysis)
Stato
lyophilized powder
Potenza
0.03-3.0 ng/mL ED50/EC50
Qualità
endotoxin tested
PM
16.4 kDa
Confezionamento
pkg of 1 μg
Condizioni di stoccaggio
avoid repeated freeze/thaw cycles
tecniche
cell culture | mammalian: suitable
Impurezze
<0.5 EU/vial
Colore
white
N° accesso UniProt
Temperatura di conservazione
−20°C
Informazioni sul gene
bovine ... FGF2(281161)
Descrizione generale
The fibroblast growth factor-2 (FGF2) gene is predominantly expressed in uterus, cornea and vascular endothelial cells. The FGF2 gene is mapped to cattle chromosome 17.
Applicazioni
A natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.
Fibroblast Growth Factor-Basic from bovine pituitary has been used:
Fibroblast Growth Factor-Basic from bovine pituitary has been used:
- In animal and human cell culture
- In neuronal induction of adipose and bone marrow-derived rat mesenchymal stem cells
- In the generation of directly reprogramming fibroblast
- In human glioma cell culture
Azioni biochim/fisiol
Fibroblast growth factor-2 (FGF2) stimulates cell proliferation, differentiation and migration. It is also known to participate in angiogenesis and carcinogenesis. During the estrous cycle, FGF2 expression is found to be maximum in porcine conceptuses and endometrium. Upregulation of this gene is also observed in pregnancy during peri-implantation. FGF2 is involved in embryogenesis, tissue repair and other metabolic pathways.
Stato fisico
Lyophilized from a 0.2 μm filtered solution in sodium phosphate and sodium chloride containing 0.1 mg bovine serum albumin
Nota sulla preparazione
Purified glands by a modification of the method of Gospodarowicz, et al.
Risultati analitici
The proliferative activity is tested in culture using fetal bovine heart endothelial cells.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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