SRP5251

PKC-α, active, GST tagged from Xanopus sp.

PRECISIO^®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Sinonimo/i: MGC82897, PRKCA
• Codice UNSPSC: 12352200
• NACRES: NA.32

Proprietà

• Origine biologica: Xenopus sp.
• Ricombinante: expressed in baculovirus infected Sf9 cells
• Nome Commerciale: PRECISIO^®
• Saggio: ≥70% (SDS-PAGE)
• Forma fisica: buffered aqueous glycerol solution
• Attività specifica: 186-290 nmol/min·mg
• PM: ~103 kDa
• N° accesso NCBI: BC078065
• applicazioni: cell analysis
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −70°C
• Informazioni sul gene: Xenopus laevis ... prkca(447031)

Descrizione

Descrizione generale

Protein kinase C-α (PKC-α) is a member of the PKC family of serine- and threonine-specific protein kinases that can be activated by calcium and the secondary messenger diacylglycerol. The protein is expressed in the dorsal ectoderm of Xenopus.

Azioni biochim/fisiol

Protein kinase C-α (PKC-α) has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint and cell volume control. It has been identified as a fundamental regulator of cardiac contractility and Ca²⁺ handling in myocytes.

Stato fisico

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Nota sulla preparazione

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Note legali

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable