SAB5701882

Anti-Phospho-VEGF Receptor 2-Y1175 antibody produced in rabbit

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: liquid
• Reattività contro le specie: human
• Concentrazione: 0.94 mg/mL
• tecniche: western blot: 1:500-1:2000
• N° accesso UniProt: P35968
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: phosphorylation (pTyr1175)
• Informazioni sul gene: human ... KDR(3791)

Descrizione

Descrizione generale

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Immunogeno

A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2.

Stato fisico

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable