Passa al contenuto
Merck
Tutte le immagini(2)

Key Documents

SAB4501645

Sigma-Aldrich

Anti-VEGFR2 antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

FLK1, KDR, kinase insert domain receptor, protein-tyrosine kinase receptor Flk-1, vascular endothelial growth factor receptor 2

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Forma fisica

buffered aqueous solution

PM

antigen 151 kDa

Reattività contro le specie

mouse, human

Concentrazione

~1 mg/mL

tecniche

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... KDR(3791)

Categorie correlate

Descrizione generale

Anti-VEGFR2 Antibody detects endogenous levels of total VEGFR2 protein.
Vascular endothelial growth factor receptor 2 (VEGFR2), also known as kinase insert domain-containing receptor (KDR), is encoded by the gene mapped to human chromosome 4q12. The encoded protein belongs to the VEGF receptor family.

Immunogeno

The antiserum was produced against synthesized peptide derived from human VEGFR2.

Immunogen Range: 917-966

Applicazioni

Anti-VEGFR2 antibody produced in rabbit has been used in histochemical analysis of hydrogels injected subcutaneously.

Azioni biochim/fisiol

Vascular endothelial growth factor receptor 2 (VEGFR2) and its ligand VEGF play a vital role in angiogenesis and inflammation. It also facilitates autocrine stimulation of VEGF. VEGFR2 is implicated in progression of various types of cancers such as gliomas, malignant peripheral nerve sheath tumors, triple-negative breast cancer (TNBC) and gastrointestinal stromal tumors (GISTs).

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Whitney L Stoppel et al.
Journal of biomedical materials research. Part A, 104(12), 3058-3072 (2016-10-28)
Heart failure is the leading cause of death in the United States and rapidly becoming the leading cause of death worldwide. While pharmacological treatments can reduce progression to heart failure following myocardial infarction, there still exists a need for new
Elastic, silk-cardiac extracellular matrix hydrogels exhibit time-dependent stiffening that modulates cardiac fibroblast response
Stoppel WL, et al.
Journal of Biomedical Materials Research Part A, 104(12), 3058-3072 (2016)
Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma
Prenen H, et al.
Oncotarget, 6(34), 36418-36418 (2015)
Molecular biology of the VEGF and the VEGF receptor family.
Clauss M
Seminars in Thrombosis and Hemostasis, 26, 561-570 (2000)
Increased Gene Copy Number of c-KIT and VEGFR2 at 4q12 in Primary Breast Cancer Is Related to an Aggressive Phenotype and Impaired Prognosis.
Johansson I, et al.
Genes Chromosomes Cancer, 51(4), 375-383 (2012)

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.