SAB4500869

Anti-CD32 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: CD32, CDW32, FC γ receptor IIB, FC-γ RII, FC-γ RII-B
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: antigen 34 kDa
• Reattività contro le specie: human, rat, mouse
• Concentrazione: ~1 mg/mL
• tecniche: ELISA: 1:1000; western blot: 1:500-1:1000
• N° accesso NCBI: P31994
• N° accesso UniProt: P31994
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... FCGR2B(2213)

Descrizione

Descrizione generale

The human immune system has six FcγRs-FcγRI, FcγRIIA, FcγRIIB, FcγRIIC, FcγRIIIA and FcγRIIIB. FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) is an inhibitory receptor that is located on human chromosome 1q23.

Anti-CD32 Antibody detects endogenous levels of total CD32 protein.

Immunogeno

The antiserum was produced against synthesized peptide derived from human CD32.

Immunogen Range: 277-326

Azioni biochim/fisiol

FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) controls the generation of autoantibodies and their effector roles. During a viral memory response, FcγRIIB blocks the generation of inflammatory type I IFN from plasmacytoid dendritic cells.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Stato fisico

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable