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Merck
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Documenti fondamentali

SAB4300251

Sigma-Aldrich

Anti-phospho-SMAD2 (pSer467) antibody produced in rabbit

affinity isolated antibody

Sinonimo/i:

Anti-JV18 antibody produced in rabbit, Anti-JV18-1 antibody produced in rabbit, Anti-MADH2 antibody produced in rabbit, Anti-MADR2 antibody produced in rabbit, Anti-SMAD family member 2 antibody produced in rabbit

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Coniugato

unconjugated

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

PM

~60 kDa

Reattività contro le specie

rat, human, mouse

Concentrazione

1 mg/mL

tecniche

western blot: 1:500-1:1000

Isotipo

IgG

Sequenza immunogenica

(C-S-S-M-SP)

N° accesso NCBI

NP_001003652.1

N° accesso UniProt

Q15796

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

phosphorylation (pSer467)

Informazioni sul gene

human ... SMAD2(4087)

Immunogeno

Peptide sequence around phosphorylation site of serine 467 (C-S-S-M-S(p)), according to the protein SMAD2.

Caratteristiche e vantaggi

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descrizione del bersaglio

Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.

Stato fisico

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
951411322

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The activation of human bronchial fibroblasts by transforming growth factor-β₁ (TGF-β₁) leads to the formation of highly contractile myofibroblasts in the process of the fibroblast⁻myofibroblast transition (FMT). This process is crucial for subepithelial fibrosis and bronchial wall remodeling in asthma.
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International journal of molecular medicine, 36(3), 801-807 (2015-07-17)
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Smooth muscle cell (SMC) migration and proliferation play an essential role in neointimal formation after vascular injury. In this study, we intended to investigate whether the X-box-binding protein 1 (XBP1) was involved in these processes. In vivo studies on femoral
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