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Documenti fondamentali

R1512

Sigma-Aldrich

Retinyl palmitate

potency: ≥1,700,000 USP units per g

Sinonimo/i:

Vitamin A palmitate, all−trans−Retinol palmitate

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About This Item

Formula empirica (notazione di Hill):
C36H60O2
Numero CAS:
Peso molecolare:
524.86
Beilstein:
1917366
Numero CE:
Numero MDL:
Codice UNSPSC:
12352205
ID PubChem:
NACRES:
NA.79

Origine biologica

synthetic (organic)

Livello qualitativo

Stato

solid or viscous liquid

Potenza

≥1,700,000 USP units per g

non contiene

antioxidant

Colore

yellow to yellow-green

Punto di fusione

26 °C

Temperatura di conservazione

2-8°C

Stringa SMILE

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+
VYGQUTWHTHXGQB-FFHKNEKCSA-N

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Categorie correlate

Descrizione generale

Retinyl palmitate or vitamin A palmitate is a retinoid, which is an acid form of vitamin A. Retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinyl palmitate is a major storage form of vitamin A found in epidermis. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.

Applicazioni

Retinyl palmitate has been used as a standard in high performance liquid chromatography (HPLC). It has also been used to study its effect on brain regeneration in larval Xenopus laevis.

Azioni biochim/fisiol

Retinyl palmitate is widely used in pharmaceutical applications. It is also extensively used in cosmetic formulations due to its beneficial effects on the appearance of skin and anti-oxidant properties. Retinyl palmitate acts as a teratogen and affect vertebrate embryogenesis and regeneration. It is added as a source of vitamin A in low fat and skim milks. Retinyl palmitate acts as a chemopreventive or antineoplastic agent.
Review: Vitamin A metabolism.

Confezionamento

Sealed ampule.

Stato fisico

oil or solid

Pittogrammi

Health hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Aquatic Chronic 3 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

No data available

Punto d’infiammabilità (°C)

No data available

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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SAFC

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Retinol esters

Ergocalciferol 40,000,000 USP units/g

Sigma-Aldrich

E5750

Ergocalciferol

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USP

1716002

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Niacinamide meets USP testing specifications

Sigma-Aldrich

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Sigma-Aldrich

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Retinolo

S D Todorov et al.
Meat science, 84(3), 334-343 (2010-04-09)
Bacteriocins bacST202Ch and bacST216Ch, produced by Lactobacillus plantarum strains isolated from Beloura and Chouriço, respectively, inhibited the growth of a number of Gram-positive and Gram-negative meat spoilage bacteria. According to trycine-SDS-PAGE, bacST202Ch and bacST216Ch are approximately 3.5 and 10.0 kDa
Fundamentals of Dairy Chemistry (2012)
The effect of retinyl-palmitate on brain regeneration of larval Xenopus laevis
Bernardini S, et al.
Italian Journal of Zoology, 77(3), 261-271 (2010)
Anticancer activity and mechanism of action of retinoids in oral and pharyngeal cancer
Klaassen I and Braakhuis BJM
Oral Oncology, 38(6) (2002)
Characterization of esterase and alcohol dehydrogenase activity in skin. Metabolism of retinyl palmitate to retinol (vitamin A) during percutaneous absorption
Boehnlein J, et al.
Pharmaceutical Research, 11(8), 1155-1159 (1994)

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