Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

N7510

Sigma-Aldrich

Nicardipine hydrochloride

powder, ≥98%

Sinonimo/i:

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-[methyl(phenylmethyl)amino]ethyl ester hydrochloride, YC-93

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C26H29N3O6 · HCl
Numero CAS:
54527-84-3
Peso molecolare:
515.99
Numero CE:
259-198-4
Numero MDL:
MFCD00057327
Codice UNSPSC:
12352200
ID PubChem:
24277856
NACRES:
NA.77

Livello qualitativo

100

Saggio

≥98%

Stato

powder

Colore

yellow

Solubilità

DMSO: ~1 mg/mL
0.1 M NaOH: insoluble
H2O: slightly soluble
methanol: soluble

Ideatore

EKR Therapeutics

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl[H].COC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OCCN(C)Cc3ccccc3

InChI

1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
AIKVCUNQWYTVTO-UHFFFAOYSA-N

Informazioni sul gene

human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Azioni biochim/fisiol

Blocks L-type voltage-dependent calcium channels; antihypertensive.

Caratteristiche e vantaggi

This compound was developed by EKR Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301 + H311 + H331

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCG9331
BCCF6860
BCCF6861
BCCF0785
BCBN3159V

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Amlodipine besylate ≥98% (HPLC)

Sigma-Aldrich

A5605

Amlodipine besylate

Lacidipine ≥98% (HPLC)

Sigma-Aldrich

SML0946

Lacidipine

Trifluoperazine hydrochloride meets USP testing specifications

Sigma-Aldrich

T6062

Trifluoperazine hydrochloride

Nicergoline analytical standard, for drug analysis

Supelco

N7889

Nicergoline

Nilotinib

Sigma-Aldrich

CDS023093

Nilotinib

Nimodipine

Sigma-Aldrich

N149

Nimodipine

vibrant-m

T3000000

Tyrothricin

S(−)-Verapamil hydrochloride hydrate ≥98% (HPLC), powder

Sigma-Aldrich

V105

S(−)-Verapamil hydrochloride hydrate

Prasanna P K M Gamage et al.
Journal of cellular and molecular medicine, 22(10), 5160-5164 (2018-07-27)
Ageing is associated with impaired neuromuscular function of the terminal gastrointestinal (GI) tract, which can result in chronic constipation, faecal impaction and incontinence. Interstitial cells of cajal (ICC) play an important role in regulation of intestinal smooth muscle contraction. However
S Thellung et al.
Neurobiology of disease, 7(4), 299-309 (2000-08-31)
Prion diseases are neurodegenerative pathologies characterized by the accumulation, in the brain, of altered forms of the prion protein (PrP), named PrP(Sc). A synthetic peptide homologous to residues 106-126 of PrP (PrP106-126) was reported to maintain the neurodegenerative characteristics of
I Japelj et al.
European journal of pharmacology, 369(1), 43-47 (1999-04-16)
The qualitative and quantitative effects of the (+)-S and (-)-R enantiomers and of the racemic mixture of the Ca2+ channel antagonist, nicardipine, were compared on the isolated porcine coronary artery with intact and removed endothelium. All three forms of nicardipine
E M Fitzgerald
The Journal of physiology, 527 Pt 3, 433-444 (2000-09-16)
The small G-protein Ras, a critical component in the signalling pathways regulating cell growth, is involved in the tonic upregulation of voltage-dependent calcium channels (VDCCs) in rat sensory neurones. To investigate which downstream effector(s) of Ras is involved in this
T Matsuda et al.
General pharmacology, 33(2), 115-125 (1999-08-26)
The effects of nicardipine and bupivacaine on early afterdepolarizations (EADs) were investigated in rabbit sinoatrial (SA) nodes using the conventional microelectrode technique. In a nominally Ca2+ -free, Mg2+ -free solution, addition of 0.5 mM Sr2+ produced EADs following prolongation of
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.