N1638

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

• Sinonimo/i: Fungicidin, Mycostatin
• Numero CAS: 1400-61-9
• Codice UNSPSC: 12352207
• ID PubChem: 24897511
• NACRES: NA.76

Proprietà

• product name: Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture
• Nome Commerciale: BioReagent
• Livello qualitativo: 200
• Forma fisica: suspension
• Concentrazione: 10,000 unit/mL in DPBS
• tecniche: cell culture | mammalian: suitable
• Impurezze: endotoxin, tested
• Colore: yellow
• Spettro attività antibiotica: fungi; yeast
• Modalità d’azione: cell membrane | interferes
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O
• InChI: 1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1; VQOXZBDYSJBXMA-QEKUPDCNSA-N

Descrizione

Descrizione generale

Chemical structure: polyene

Applicazioni

Nystatin suspension has been used:

• to inhibit caveolin-mediated endocytosis
• as a component of Eagle′s minimum essential medium (EMEM)
• to enumerate lactic acid bacteria (LAB)
• in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.

This product is recommended for use in cell culture applications at 24 mL/L.

Azioni biochim/fisiol

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

Avvertenza

This product is stable at 37°C for three days.

Nota sulla preparazione

It is 0.1μ filtered and cell culture tested.

Altre note

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable