MAK107
LCAT Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Sinonimo/i:
Lecithin:cholesterol acyltransferase activity assay kit
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About This Item
Prodotti consigliati
impiego
sufficient for 100 fluorometric tests
applicazioni
pharmaceutical
Metodo di rivelazione
fluorometric
Malattie correlate
cardiovascular diseases
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... LCAT(3931)
Descrizione generale
The plasma protein lecithin:cholesterol acyltransferase (LCAT) catalyzes the transfer of an acyl group from the sn2 position of phosphatidylcholine to the 3-hydroxyl group of cholesterol resulting in the formation cholesteryl ester. This enzymatic activity occurs on the surface of high density lipoprotein (HDL). The cholesteryl esters formed by LCAT may be packed into the core of HDL.
Applicazioni
Applications for this method include high-throughput screening, mechanism of action studies and structure-activity relationship (SAR) work.
LCAT Activity Assay Kit has been used for measuring lecithin-cholesterol acyl transferase activity in plasma samples.
Caratteristiche e vantaggi
Compatible with high-throughput handling systems.
Compatibilità
Suitable for measuring phospholipase activity of LCAT in plasma or serum.
Principio
The LCAT Activity Assay Kit is a fluorometric assay useful for measuring phospholipase activity of (λEx=390 nm/λEm=470 nm) LCAT. The assay may be validated by inhibition of LCAT with iodoacetate or another spectrally benign (not Ellman′s reagent) LCAT inhibitor.
Risultati analitici
Solo come componenti del kit
N° Catalogo
Descrizione
- Substrate Reagent .1 mL
- READ Reagent 30 mL
- LCAT Assay Buffer 20 mL
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Codice della classe di stoccaggio
3 - Flammable liquids
Punto d’infiammabilità (°F)
49.5 °F
Punto d’infiammabilità (°C)
9.7 °C
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