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M6517

Sigma-Aldrich

α,β-Methyleneadenosine 5′-triphosphate lithium salt

≥93% (HPLC), solid

Sinonimo/i:

AMP-CPP

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About This Item

Formula empirica (notazione di Hill):
C11H18N5O12P3 · xLi+
Numero CAS:
104809-20-3
Peso molecolare:
505.21 (free acid basis)
Numero MDL:
MFCD00148925
Codice UNSPSC:
41106305
eCl@ss:
32160414
ID PubChem:
24277720
NACRES:
NA.77

Livello qualitativo

200

Saggio

≥93% (HPLC)

Stato

solid

Colore

white

Solubilità

H2O: 100 mg/mL

Temperatura di conservazione

−20°C

Stringa SMILE

[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)CP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C11H18N5O12P3.Li/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25;/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25);/q;+1/p-1/t5-,7-,8-,11-;/m1./s1
NVHVREPTGDOYIC-YCSZXMBFSA-M

Informazioni sul gene

human ... P2RX1(5023)

Categorie correlate

Applicazioni

α,β-Methyleneadenosine 5′-triphosphate lithium salt has been used:
  • as P2-purinoreceptor agonist (P2X), to analyse its effects on membrane conductance in the astrocytes of caudal nucleus
  • as a P2X receptor agonist, to increase the calcium current in the neurons in satellite cells
  • to determine the functional sensitivities of purinergic agonists on P2Y receptors in rat and to determine its effect on developing outer sulcus cells

Azioni biochim/fisiol

P2 purinoceptor agonist that is more potent than ATP at the P2X subtype.

Caratteristiche e vantaggi

This compound is featured on the P2 Receptors: P2X Ion Channel Family and P2 Receptors: P2Y G-Protein Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Stato fisico

hygroscopic solid

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
SLCJ7725
SLCF0256
SLBZ4565
SLBX8729
SLBP7887V

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DNA polymerase delta (Pol δ) is responsible for the elongation and maturation of Okazaki fragments in eukaryotic cells. Proliferating cell nuclear antigen (PCNA) recruits Pol δ to the DNA and serves as a processivity factor. Here, we show that PCNA
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Neuroscience Letters, 584, 168-172 (2015)
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