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Merck
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Documenti

M1514

Sigma-Aldrich

Nω-Methyl-5-hydroxy­trypt­amine oxalate salt

≥90% (HPLC)

Sinonimo/i:

Nω-Methylserotonin oxalate salt

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About This Item

Formula empirica (notazione di Hill):
C11H14N2O · C2H2O4
Numero CAS:
1975-81-1
Peso molecolare:
280.28
Numero MDL:
MFCD00013159
Codice UNSPSC:
12352116
ID PubChem:
24278536
NACRES:
NA.77

Saggio

≥90% (HPLC)

Temperatura di conservazione

2-8°C

Stringa SMILE

OC(=O)C(O)=O.CNCCc1c[nH]c2ccc(O)cc12

InChI

1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)
DYOZWAJOUTVNAF-UHFFFAOYSA-N

Informazioni sul gene

human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)

Azioni biochim/fisiol

Serotonin receptor ligand.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Niels Hadrup et al.
Drug and chemical toxicology, 42(1), 76-83 (2018-07-24)
Selenium (Se) nanoparticles have been proposed as food supplements. However, the particle formulation may exert unexpected toxicity. The aim was therefore to compare toxicity of low doses of Se nanoparticles and the dissolved, ionized Se species selenite. Female rats were
C R Ashby et al.
Synapse (New York, N.Y.), 17(3), 173-181 (1994-07-01)
In this study, we examined the interaction of 5-HT1A and 5-HT2A receptors in the rat medial prefrontal cortex (mPFc) using the techniques of extracellular single unit recording and microiontophoresis. The iontophoresis of the selective 5-HT1A receptor agonist (+-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-OHDPAT)
Albrecht Pfäfflin et al.
Annals of clinical biochemistry, 46(Pt 2), 146-148 (2009-01-20)
Serotonin is frequently analysed by high-performance liquid chromatography (HPLC) with electrochemical detection. However, the accuracy of these methods may be affected by the presence of certain drugs. We describe for the first time the interference of paracetamol in therapeutic dosages
Simultaneous micro-determination of serotonin and 5-hydroxyindole-3-acetic acid with 5-hydroxy-N omega-methyltryptamine, as an internal standard, in biological materials by high-performance liquid chromatography with electrochemical detection.
K Shibata et al.
Journal of chromatography, 430(2), 381-387 (1988-09-09)
P M Lalley et al.
The Journal of physiology, 487 ( Pt 3), 653-661 (1995-09-15)
1. The effects of the 5-HT2 receptor agonist alpha-methyl-5-HT were studied on the membrane of expiratory (E2) and post-inspiratory (PI) neurones, by intracellular recordings in the caudal medulla of anaesthetized cats. 2. Ionophoresis of alpha-Me-5-HT depolarized membrane potential and increased
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